Research Fellow (Single-molecule biophysics)

About This Role

Seeking a PhD researcher to lead an independent project on biomolecular condensates regulating enzyme function using single-molecule spectroscopy.

Responsibilities

• Spearhead an independent project decoding how biomolecular condensates regulate enzyme function.
• Design and validate novel molecular probes or synthetic condensates using genetic engineering.
• Apply advanced single-molecule spectroscopy methods to measure molecular dynamics in vitro and in cell.
• Drive the publication of high-impact findings through scientific papers and conference presentations.

Requirements

• PhD in biophysics, biochemistry, molecular biology, or cell biology.
• Strong track record of experimentation and quantitative thinking.
• Demonstrated ability to analyze complex datasets and communicate results clearly.
• Strong motivation, reliability, and ability to work independently or with a team.
• Experience with single-molecule spectroscopy techniques (e.g., smFRET, FCS).
• Expertise in protein/DNA biochemistry including labelling strategies and activity assays.
• Experience with live-cell imaging or microfluidics.