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A*STAR
A*STAR

Research Scientist (SXY Lab), IMCB

Institute of Molecular & Cell Biology

Location

Singapore

Department

Institute of Molecular & Cell Biology

Posted

2 months before

Full Job Description

Job Description

  • Develop and apply human stem cell-derived retinal epithelial and endothelial cells for therapeutic screening.
  • Evaluate therapeutic uptake, trafficking, and knockdown efficiency using advanced molecular and cellular assays.
  • Build and apply functional assays (e.g. migration, tube formation) to assess therapeutic outcomes
  • Test lead candidates in preclinical mouse models, evaluating biodistribution and efficacy through various delivery routes
  • Collaborate with a dynamic, multidisciplinary team, contributing to publications, presentations, and translational milestones.
  • Drive reporting outputs including progress updates, invention disclosures, and final research reports.

Job Requirements

  • PhD in Biology, Biomedical Science, Biotechnology, or related field (or equivalent experience).
  • Strong background in stem cell biology, with experience in epithelial or vascular endothelial differentiation is preferred.
  • Expertise in cellular and molecular techniques (e.g. qPCR, immunofluorescence, confocal microscopy, flow cytometry).
  • Experience in in-vitro and in-vivo (rodent) disease modelling is highly preferred.
  • Proven ability to design, execute, and analyze complex experiments with attention to detail.
  • Strong communication skills and a collaborative mindset, with a track record of scientific writing or high impact publication.