A*STAR

Scientist, Infectious Diseases

A*STAR
ResearchSingaporeOnsitePosted 5 days ago

About the role

The Scientist (Bioinformatician, Pathogen Annotation) provides expertise in pathogen genomics to support a genomic surveillance platform, developing and maintaining annotation tools, defining standards, benchmarking pipelines, and collaborating with engineers and curators to ensure high‑quality data for public health.

ResearchOnsiteA*STAR Infectious Disease Labs

Key Responsibilities

  • Adapt and maintain annotation and analysis tools for new pathogens, aligned with biological context and standards
  • Translate pathogen biology into requirements for pipelines, dashboards, and visualisations
  • Define annotation rules, quality thresholds, and exception handling with curators and bioinformaticians
  • Benchmark tools and workflows against reference datasets and external resources
  • Collaborate with engineers to drive feature enhancements and performance improvements
  • Monitor outputs to detect anomalies and ensure data quality across pathogens

Requirements

  • PhD in Bioinformatics, Computational Biology, Microbiology, Virology, or related field
  • Strong grounding in pathogen genomics and genome organisation
  • Familiarity with genome annotation, reference genomes, and comparative genomics
  • Experience with sequence formats (FASTA, GFF/GTF) and metadata standards
  • Proficiency in Unix/Linux, Git, and scripting (Python or R)
  • Experience designing and interpreting validation/benchmarking of bioinformatics tools